Particle and Fibre Toxicology

Table 3 Flow cytometry analysis of association between PM₁₀ exposure (Day −1) and cell-specific EV count, after BMI stratification and adjustment for age, sex, smoking status, and apparent temperature

From: Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

	Overweight (25 ≤ BMI < 30 kg/m²)			Obese (BMI ≥ 30 kg/m²)			P for Interaction
EV type	Δ%^a	95% CI	P	Δ%	95% CI	P	P for Interaction
CD61+ (platelets)	7.58	0.96; 14.62	0.0249	4.65	0.74; 8.70	0.0195	0.4531
CD66+ (neutrophils)	5.48	0.68; 10.51	0.0257	0.53	−2.45; 3.60	0.7305	0.0881
EpCAM+ (epithelium)	8.11	2.22; 14.34	0.0068	0.93	−2.34; 4.31	0.5833	0.0263
CD105+ (endothelium)	5.09	0.51; 9.88	0.0298	0.70	−1.91; 3.38	0.6012	0.0826
CD14+ (macrophages/monocytes)	12.04	5.93; 18.51	0.0001	1.51	−2.05; 5.19	0.4119	0.0032

^aΔ% = (exp (β*10)-1)*100, percentage increase in EV count for each 10-μg/m³ increase in PM₁₀ concentration

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ISSN: 1743-8977

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