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Table 3 Flow cytometry analysis of association between PM10 exposure (Day −1) and cell-specific EV count, after BMI stratification and adjustment for age, sex, smoking status, and apparent temperature

From: Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

  Overweight (25 ≤ BMI < 30 kg/m2) Obese (BMI ≥ 30 kg/m2) P for Interaction
EV type Δ%a 95% CI P Δ% 95% CI P
CD61+ (platelets) 7.58 0.96; 14.62 0.0249 4.65 0.74; 8.70 0.0195 0.4531
CD66+ (neutrophils) 5.48 0.68; 10.51 0.0257 0.53 −2.45; 3.60 0.7305 0.0881
EpCAM+ (epithelium) 8.11 2.22; 14.34 0.0068 0.93 −2.34; 4.31 0.5833 0.0263
CD105+ (endothelium) 5.09 0.51; 9.88 0.0298 0.70 −1.91; 3.38 0.6012 0.0826
CD14+ (macrophages/monocytes) 12.04 5.93; 18.51 0.0001 1.51 −2.05; 5.19 0.4119 0.0032
  1. aΔ% = (exp (β*10)-1)*100, percentage increase in EV count for each 10-μg/m3 increase in PM10 concentration