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Table 4 Association between PM10 exposure (Day −1) and levels of validated miRNAs in EVs, after adjustment for age, sex, BMI, smoking status, and apparent temperature

From: Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

miRNA name

Δ%a

95% CI

P

hsa-miR-218-5p

−4.20

−1.87; −6.47

0.0005

hsa-miR-99b-5p

−3.14

−0.56; −5.65

0.0173

hsa-let-7c-5p

−2.72

−0.31; −5.08

0.0270

hsa-miR-331-3p

−3.07

−0.26; −5.80

0.0328

hsa-miR-185-5p

−2.78

−0.19; −5.31

0.0359

hsa-miR-642-5p

−3.51

−0.17; −6.74

0.0397

hsa-miR-106a-5p

−2.59

[−0.11; −5.01]

0.0409

hsa-miR-143-3p

−2.75

[−0.04; −5.39]

0.0467

hsa-miR-652-3p

−2.69

[−0.03; −5.29]

0.0478

  1. aΔ% = (2 (β*10)-1)*100, percentage increase in EV count for each 10 μg/m3 increase in PM10 concentration