Fig. 2

IMP pre-treatment effect on acute inflammation induced by silica. Mice were treated with IMP or PBS for 30 min, then exposed to silica or vehicle. Whole lung lavage was collected after 24 h. a Total number of cells in the lavage fluid. b Polymorphonuclear (PMN) leukocytes in lavage were assessed by staining. c IL-1β levels in lavage fluid. d IL-1β in supernatant of isolated AM exposed to LPS ex vivo for an additional 24 h. n ≥ 3 mice per treatment condition