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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Imipramine blocks acute silicosis in a mouse model

Fig. 9

Therapeutic effect of IMP on lung injury and collagen accumulation during post-administration ten-week study. Mice were exposed to silica or vehicle weekly for the first four weeks, then received IMP or PBS by osmotic pump for remaining six weeks. a Total protein levels in lavage fluid as an indicator of lung injury. b Hydroxyproline in lungs as an indicator of collagen accumulation. n ≥ 3 mice per treatment condition

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Particle and Fibre Toxicology

ISSN: 1743-8977

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