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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials

Fig. 6

Biokinetics study results. Percent of applied (apical compartment) Fe2O3 in cells + membrane and basolateral compartments following incubation of transwell triculture inserts for the times indicated with digesta diluted 1:3 in DMEM with or without FBS as indicated. a 2 or 4 h incubations with digesta (0.1 wt% Fe2O3 in initial food emulsion) diluted with DMEM +10% FBS b 2 or 4 h incubations with digesta (0.1 wt% Fe2O3 in initial food emulsion) diluted with DMEM without FBS. c 4 h incubations with digesta from emulsions containing 0.05 or 0.1 wt% Fe2O3, diluted 1:3 with DMEM without FBS

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