Fig. 6From: An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterialsBiokinetics study results. Percent of applied (apical compartment) Fe2O3 in cells + membrane and basolateral compartments following incubation of transwell triculture inserts for the times indicated with digesta diluted 1:3 in DMEM with or without FBS as indicated. a 2 or 4Â h incubations with digesta (0.1Â wt% Fe2O3 in initial food emulsion) diluted with DMEM +10% FBS b 2 or 4Â h incubations with digesta (0.1Â wt% Fe2O3 in initial food emulsion) diluted with DMEM without FBS. c 4Â h incubations with digesta from emulsions containing 0.05 or 0.1Â wt% Fe2O3, diluted 1:3 with DMEM without FBSBack to article page