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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo

Fig. 3

Analysis of phosphatidilserine (PS) translocation and membrane permeabilisation by flow cytometry. The indicated cells were mock treated (ctrl) or incubated with four types of nanoparticles (NPR-P, NPR-PG, NPR-PT, NPR-PTG) at four different concentrations (25, 50, 100 and 200 μg/mL) for 48 h and PS translocation and membrane permeabilisation were monitored using annexin-V and 7AAD respectively as indicated in experimental section. As positive control (C+) staurosporin 1 μM was used. (a) Data represent mean values ± SD from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001. (b). A representative experiment is shown at the concentration of 100 μg/mL. Numbers correspond to the percentage of cells in each quadrant

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Particle and Fibre Toxicology

ISSN: 1743-8977

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