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Table 2 Quantification of corona proteins on nanoparticles (A. μg/mg NPs; B. µg/m2 NPs)

From: Protein corona: implications for nanoparticle interactions with pulmonary cells

 

CeO2

Si-CeO2

BaSO4

ZnO

A.

 C3

0.46 ± 0.19

0.47 ± 0.12*

0.63 ± 0.27

1.21 ± 0.37*

 Cfb

0.48 ± 0.25#

0.71 ± 0.26*

0.98 ± 0.31

1.54 ± 0.35*#

 Tf

0.60 ± 0.39#

0.84 ± 0.23*

1.67 ± 0.36

2.57 ± 0.95*#

 Albumin

0.78 ± 0.54*#

1.47 ± 0.66@

2.79 ± 0.27*

3.38 ± 0.79#@

 A1AT

0.74 ± 0.45*

1.21 ± 0.17#

1.98 ± 0.49

2.91 ± 0.72*#

 Tubb2A

0.72 ± 0.49*

1.20 ± 0.26#

1.57 ± 0.14

2.29 ± 0.52*#

 SP-D

0.65 ± 0.40*

1.23 ± 0.34

1.61 ± 0.37

2.35 ± 0.63*

 SP-A

0.80 ± 0.46*

1.48 ± 0.31

1.82 ± 0.29

2.89 ± 1.24*

 PLUNC

0.72 ± 0.38*

1.17 ± 0.20

1.51 ± 0.28

2.23 ± 0.66*

 Others

4.17 ± 1.73

4.20 ± 0.94

4.11 ± 3.37

8.18 ± 2.52

B.

 C3

0.16 ± 0.07

0.17 ± 0.04

0.18 ± 0.08

0.29 ± 0.09

 Cfb

0.17 ± 0.09

0.25 ± 0.09

0.28 ± 0.09

0.38 ± 0.08

 Tf

0.22 ± 0.14*

0.30 ± 0.08

0.48 ± 0.10

0.63 ± 0.23*

 Albumin

0.28 ± 0.19*#

0.53 ± 0.24

0.81 ± 0.08*

0.82 ± 0.19#

 A1AT

0.26 ± 0.16*

0.44 ± 0.06

0.57 ± 0.14

0.71 ± 0.18*

 Tubb2A

0.26 ± 0.18@

0.43 ± 0.09

0.45 ± 0.04

0.56 ± 0.13@

 SP-D

0.23± 0.14@

0.44 ± 0.12

0.47 ± 0.11

0.57 ± 0.15@

 SP-A

0.29 ± 0.16

0.53 ± 0.11

0.53 ± 0.08

0.71 ± 0.30

 PLUNC

0.26 ± 0.14

0.42 ± 0.07

0.44 ± 0.08

0.54 ± 0.16

 Others

1.49 ± 0.62

1.51 ± 0.34

1.19 ± 0.97

2.00 ± 0.61

  1. Data are mean ± SD of triplicate analyses using pooled BALf from 3 rats per NP
  2. The pair of NPs with *, # or @ are significantly different from each other, P < 0.05, Tukey adjustment for multiple comparisons
  3. C3 complement component 3, Cfb complement factor B, Tf transferrin, A1AT α1-antitrypsin, Tubb2A Tubulin Beta 2A Class IIa, SP-D Surfactant protein-D, SP-A Surfactant protein-A, PLUNC Palate, lung, nasal epithelium clone protein