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Table 2 Quantification of corona proteins on nanoparticles (A. μg/mg NPs; B. µg/m2 NPs)

From: Protein corona: implications for nanoparticle interactions with pulmonary cells

  CeO2 Si-CeO2 BaSO4 ZnO
A.
 C3 0.46 ± 0.19 0.47 ± 0.12* 0.63 ± 0.27 1.21 ± 0.37*
 Cfb 0.48 ± 0.25# 0.71 ± 0.26* 0.98 ± 0.31 1.54 ± 0.35*#
 Tf 0.60 ± 0.39# 0.84 ± 0.23* 1.67 ± 0.36 2.57 ± 0.95*#
 Albumin 0.78 ± 0.54*# 1.47 ± 0.66@ 2.79 ± 0.27* 3.38 ± 0.79#@
 A1AT 0.74 ± 0.45* 1.21 ± 0.17# 1.98 ± 0.49 2.91 ± 0.72*#
 Tubb2A 0.72 ± 0.49* 1.20 ± 0.26# 1.57 ± 0.14 2.29 ± 0.52*#
 SP-D 0.65 ± 0.40* 1.23 ± 0.34 1.61 ± 0.37 2.35 ± 0.63*
 SP-A 0.80 ± 0.46* 1.48 ± 0.31 1.82 ± 0.29 2.89 ± 1.24*
 PLUNC 0.72 ± 0.38* 1.17 ± 0.20 1.51 ± 0.28 2.23 ± 0.66*
 Others 4.17 ± 1.73 4.20 ± 0.94 4.11 ± 3.37 8.18 ± 2.52
B.
 C3 0.16 ± 0.07 0.17 ± 0.04 0.18 ± 0.08 0.29 ± 0.09
 Cfb 0.17 ± 0.09 0.25 ± 0.09 0.28 ± 0.09 0.38 ± 0.08
 Tf 0.22 ± 0.14* 0.30 ± 0.08 0.48 ± 0.10 0.63 ± 0.23*
 Albumin 0.28 ± 0.19*# 0.53 ± 0.24 0.81 ± 0.08* 0.82 ± 0.19#
 A1AT 0.26 ± 0.16* 0.44 ± 0.06 0.57 ± 0.14 0.71 ± 0.18*
 Tubb2A 0.26 ± 0.18@ 0.43 ± 0.09 0.45 ± 0.04 0.56 ± 0.13@
 SP-D 0.23± 0.14@ 0.44 ± 0.12 0.47 ± 0.11 0.57 ± 0.15@
 SP-A 0.29 ± 0.16 0.53 ± 0.11 0.53 ± 0.08 0.71 ± 0.30
 PLUNC 0.26 ± 0.14 0.42 ± 0.07 0.44 ± 0.08 0.54 ± 0.16
 Others 1.49 ± 0.62 1.51 ± 0.34 1.19 ± 0.97 2.00 ± 0.61
  1. Data are mean ± SD of triplicate analyses using pooled BALf from 3 rats per NP
  2. The pair of NPs with *, # or @ are significantly different from each other, P < 0.05, Tukey adjustment for multiple comparisons
  3. C3 complement component 3, Cfb complement factor B, Tf transferrin, A1AT α1-antitrypsin, Tubb2A Tubulin Beta 2A Class IIa, SP-D Surfactant protein-D, SP-A Surfactant protein-A, PLUNC Palate, lung, nasal epithelium clone protein