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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Sub-chronic inhalation of lead oxide nanoparticles revealed their broad distribution and tissue-specific subcellular localization in target organs

Fig. 9

Immunostaining of kidney samples following 6 weeks exposure to PbO-NPs. a-c PCNA in kidney tissue. Arrows indicate PCNA-positive cells in kidney. An enormous amount of positive cells is in infiltrates. d-f TUNEL in kidney tissue. Arrows indicate TUNEL-positive cells, individually located mostly in infiltrates. g-i Na-K ATPase in control samples. Cells with high positivity of enzyme are epithelial cells of distal tubules. j-l Na-K ATPase in treated samples. Arrows indicate decreased activity of enzyme in the epithelial cells of proximal tubules. Scale bar in all panels = 100 μm

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Particle and Fibre Toxicology

ISSN: 1743-8977

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