Fig. 4
From: Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice
Enhanced darkfield (a-c) and brightfield (d) pictures of H&E stained liver tissue from intravenously (IV) and intratracheally (IT) exposed mice that received control vehicle (a) or 162 μg/animal of TiO2 (b), CeO2 (c) or CB (d) NPs 180 days post-exposure. In the liver sections of mice exposed to TiO2 and CeO2 light scattering aggregates were observed using enhanced darkfield microscopy (b and c, selected NPs marked with white arrowheads). In the liver sections of mice exposed to CB NPs black aggregates were observed using brightfield microscopy (d, selected NPs marked with black arrowheads)