Fig. 1
a. OVA-specific IgE in serum. b. OVA-specific IgG1 in serum. Mice were sensitized with OVA alone, OVA + rutile TiO 2 NP, OVA + anatase TiO 2 NP, or OVA + Carbon Black (CB), and challenged with OVA. N = 6, mean ± SEM is shown. (*), (**), and (***) P < 0.05, P < 0.01, and P < 0.001vs. OVA alone; (+), (++), and (+++) P < 0.05, P < 0.01, and P < 0.001 vs. OVA + rutile NP; (###) P < 0.001 vs. OVA + anatase NP