| |
NTA
|
|---|
|
Mean (nm)
|
Mode (nm)
|
D10 (nm)
|
D50 (nm)
|
D90 (nm)
|
|---|
|
Ex vivo Study
|
|
E171
|
203 ± 75
|
264 ± 135
|
77 ± 69
|
179 ± 84
|
363 ± 126
|
|
Aeroxide P25
|
101 ± 58
|
128 ± 120
|
27 ± 17
|
79 ± 56
|
204 ± 121
|
|
E153
|
204 ± 58
|
291 ± 130
|
79 ± 45
|
192 ± 70
|
340 ± 112
|
|
Printex 90
|
166 ± 27
|
224 ± 119
|
35 ± 20
|
13 ± 20
|
339 ± 72
|
|
In vivo Study
|
|
E171
|
270 ± 25
|
298 ± 58
|
163 ± 19
|
266 ± 28
|
374 ± 26
|
|
E153
|
230 ± 24
|
227 ± 61
|
137 ± 17
|
211 ± 24
|
347 ± 33
|
- Hydrodynamic size distribution of particles used in the ex vivo and the in vivo study was measured by the Nanoparticle Tracking Analysis (NTA). The data are expressed as the mean, mode, distribution fractions D10, D50 and D90, ± SD. Each experiment was repeated three times on different days
