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Table 2 Hydrodynamic particle size of E171 and E153 in suspension vehicle for the ex vivo and in vivo studies

From: Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

 

NTA

Mean (nm)

Mode (nm)

D10 (nm)

D50 (nm)

D90 (nm)

Ex vivo Study

E171

203 ± 75

264 ± 135

77 ± 69

179 ± 84

363 ± 126

Aeroxide P25

101 ± 58

128 ± 120

27 ± 17

79 ± 56

204 ± 121

E153

204 ± 58

291 ± 130

79 ± 45

192 ± 70

340 ± 112

Printex 90

166 ± 27

224 ± 119

35 ± 20

13 ± 20

339 ± 72

In vivo Study

E171

270 ± 25

298 ± 58

163 ± 19

266 ± 28

374 ± 26

E153

230 ± 24

227 ± 61

137 ± 17

211 ± 24

347 ± 33

  1. Hydrodynamic size distribution of particles used in the ex vivo and the in vivo study was measured by the Nanoparticle Tracking Analysis (NTA). The data are expressed as the mean, mode, distribution fractions D10, D50 and D90, ± SD. Each experiment was repeated three times on different days
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Particle and Fibre Toxicology

ISSN: 1743-8977

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