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Table 2 Hydrodynamic particle size of E171 and E153 in suspension vehicle for the ex vivo and in vivo studies

From: Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

  NTA
Mean (nm) Mode (nm) D10 (nm) D50 (nm) D90 (nm)
Ex vivo Study
E171 203 ± 75 264 ± 135 77 ± 69 179 ± 84 363 ± 126
Aeroxide P25 101 ± 58 128 ± 120 27 ± 17 79 ± 56 204 ± 121
E153 204 ± 58 291 ± 130 79 ± 45 192 ± 70 340 ± 112
Printex 90 166 ± 27 224 ± 119 35 ± 20 13 ± 20 339 ± 72
In vivo Study
E171 270 ± 25 298 ± 58 163 ± 19 266 ± 28 374 ± 26
E153 230 ± 24 227 ± 61 137 ± 17 211 ± 24 347 ± 33
  1. Hydrodynamic size distribution of particles used in the ex vivo and the in vivo study was measured by the Nanoparticle Tracking Analysis (NTA). The data are expressed as the mean, mode, distribution fractions D10, D50 and D90, ± SD. Each experiment was repeated three times on different days