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Table 1 MCP230 exposure results in pulmonary Th17 associated cytokine induction

From: Radical containing combustion derived particulate matter enhance pulmonary Th17 inflammation via the aryl hydrocarbon receptor

  MCP230
Cytokines 12 h 1 d
IL1β 1.446 ± 0.1729 1.691 ± 0.2082a
IL6 45.71 ± 8.457a 10.61 ± 3.177a
IL21 0.7346 ± 0.0256 1.034 ± 0.1367
IL17A 0.6526 ± 0.1302 6.096 ± 1.666a
IL22 0.9377 ± 0.0325 1.504 ± 0.158a
IL17E 0.7034 ± 0.0941 0.9023 ± 0.0322
KC 5.629 ± 1.54 p = 0.053 2.591 ± 0.4729a
MCP-1 6.337 ± 1.325a 6.825 ± 0.2238a
IL33 2.226 ± 0.1384a 2.716 ± 0.1907a
IL31 0.3472 ± 0.07782a 0.4988 ± 0.0489
  1. Levels of Th17 cytokines were determined in the lung homogenates of WT mice exposed to MCP230 at 12 h and 1 day post-exposure. Concentrations (pg/mg of lung protein) of all cytokines were measured using multiplex assay. Data are expressed as means ± SEM of fold change over Vehicle treated controls from 4 to 5 mice. ap < 0.05 compared to vehicle control, unpaired t test