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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Fig. 2

Release and mRNA expression of inflammatory biomarkers in models after exposure to diesel exhaust particles (DEP). Levels of CXCL-8 (a) and IL-6 (c) secretion in basal medium in PBEC-ALI and PBEC-AL/MQ (N = 9) after exposure to DEP and incubated for 24 h; Fold change of CXCL8 (b), IL6 (d) and TNFα (e) expression in PBEC-ALI and PBEC-AL/MQ(N = 6) after exposure to DEP and incubated for 24 h; Exposure: sham: clean air; DEP: 12.7 μg/cm2; Data presented as median and 25th -75thpercentiles, fold change =2-ΔCt of models / 2-ΔCt of sham exposed PBEC-ALI; *: P < 0.05 VS Sham exposure; #: P < 0.05 VS PBEC-ALI

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