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Table 4 LOAELs (in μg/cm2 for 24 h of exposure) determined for pro-inflammatory effects

From: Predicting the in vivo pulmonary toxicity induced by acute exposure to poorly soluble nanomaterials by using advanced in vitro methods

  1. Significant effects allowing the determination of a LOAEL
  2. No significant adverse effects observed
  3. aDoses tested at the ALI: 0.1, 1, 3 μg/cm2
  4. bDoses tested in submerged conditions in inserts: 1, 3, 10 μg/cm2
  5. cDoses tested in submerged conditions in plates: 1, 3, 10, 20 μg/cm2
  6. dDoses tested in vivo: 0.001, 0.01, 0.1 μg/cm2