Fig. 8
Effect of iron chelator and calcium modulators on cytotoxicity. The percentage of apoptotic (a) and necrotic (b) cells as evaluated by CBMN Cyt assay following co-exposures of 5 μg Ni/mL Ni, NiO or NiCl2 with deferoxamine, verapamil, dantrolene or BAPTA-AM for 48 h. Results are presented as mean ± SEM from three independent experiments (n = 3). *, p < 0.05; **, p < 0.01; ***, p < 0.001