Fig. 9From: Calcium-dependent cyto- and genotoxicity of nickel metal and nickel oxide nanoparticles in human lung cellsSummary of main results. Ni NPs, NiO NPs and ionic Ni (NiCl2) caused chromosomal damage that was dependent on Ca2+. Changes in cytosolic Ca2+ can take place by entry through plasma membrane Ca2+ channels, release of Ca2+ from the endoplasmic reticulum (ER) or release from the mitochondria via opening of the mitochondrial permeability transition poreBack to article page