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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Genotoxic and epigenotoxic effects in mice exposed to concentrated ambient fine particulate matter (PM2.5) from São Paulo city, Brazil

Fig. 2

Representative chromatograms of DNA samples obtained by HPLC-ESI-MS/MS showing a 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo); b 1,N2-etheno-2′-deoxyguanosine (1,N2-εdGuo) and 1,N6-etheno-2′-deoxyadenosine (1,N6-εdAdo); c 5-methyl-2′-deoxycytidine (5-mC), 5-hydroxymethyl-2′-deoxycytidine (5-hmC), and 2′-deoxycytidine (dCyd). The analyses were performed with multiple reaction monitoring (MRM) by using the fragmentations specified in the images for each analyte. The internal standards are represented by the red traces

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