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Table 3 Enzymatic activities of glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), superoxide dismutase (SOD), and catalase (CAT) in lung, liver, kidney (U/μg protein), and erythrocytes (U/g hemoglobin)

From: Genotoxic and epigenotoxic effects in mice exposed to concentrated ambient fine particulate matter (PM2.5) from São Paulo city, Brazil

 

Ambient Air

PM2.5

Number

P value

Average ± SEM

(U/μg protein or U/g hemoglobin)

Average ± SEM

(U/μg protein or U/g hemoglobin)

Lung

 GPx

2.832 ± 0.083

2.967 ± 0.114

4

NS

 GR

1.454 ± 0.047

1.142 ± 0.074

4

0.02

 GST

12.96 ± 0.600

12.96 ± 0.480

4

NS

 SOD

133,436 ± 5858

190,269 ± 13,951

4

0.02

Liver

 GPx

9.900 ± 0.110

10.11 ± 0.150

5

NS

 GR

1.390 ± 0.040

1.350 ± 0.060

5

NS

 GST

31.82 ± 1.040

35.25 ± 0.700

5

0.02

 SOD

296,609 ± 37,767

142,425 ± 21,046

5

<0.01

Kidney

 GPx

6.540 ± 0.090

6.170 ± 0.230

5

NS

 GR

3.110 ± 0.080

2.910 ± 0.140

5

NS

 GST

13.37 ± 0.240

13.020 ± 0.570

5

NS

 SOD

114,203 ± 7149

109,789 ± 17,576

5

NS

Erythrocytes

 GPx

2175 ± 72.00

2292 ± 63.00

6

NS

 GR

103.8 ± 4.500

97.98 ± 3.070

5

NS

 GST

168.0 ± 7.900

173.8 ± 3.800

4

NS

 SOD

151,304 ± 14,350

216,638 ± 4807

4

<0.01

 CAT

110,883 ± 5300

113,442 ± 3196

6

NS

  1. NS Not Significant