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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Chronic pulmonary exposure to traffic-related fine particulate matter causes brain impairment in adult rats

Fig. 3

Magnetic resonance imaging (MRI) analysis of rat brains in the control, high-efficiency particulate air (HEPA), and particulate matter with an aerodynamic diameter of < 1 μm (PM1) groups (n = 9). The whole brain volume, hippocampal volume, and hippocampus to whole brain volume (%) were measured after 3 and 6 months of exposure. Whole brain volumes (nm3) of rats exposed to PM1 for 3 months and to HEPA and PM1 for 6 months were significantly larger than those of the control. Hippocampal brain volumes (nm3) of rats exposed to HEPA and PM1 for 6 months were significantly larger than those of the control. * p < 0.05

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