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Table 1 Documented cytokine secretion profiles for pulmonary cells or tissues following exposure to biodiesel emissions

From: The potential of omics approaches to elucidate mechanisms of biodiesel-induced pulmonary toxicity

Study Malorni et al. 2017 [92] Fukagawa et al. 2013 [29] Yanamala et al. 2013 [65] Shvedova et al. 2013 [90]
Exposure 20% FAME PM0.1 (organic fraction) 20% SME
Total PM
100% FAME
Total PM
100% SME
Total PM
Model A549 THP-1 BEAS-2B Mouse lung Mouse BALF Mouse lung Mouse BALF Mouse Lung
bFGF N N N
CCL5 (RANTES) N N N N N N
CXCL1 (KC) N N N N
CXCL9 (MIG) N N N N N N
Eotaxin N N N
G-CSF N
GM-CSF N
IL-10
IL-12p40 N N N
IL-12p70
IL-13 N
IL-15 N
IL-17 N
IL-18 N N N N N N
IL-1α N N N N
IL-1β N
IL-1ra N N N N N
IL-2 N
IL-3 N N N N N N
IL-4 N
IL-5 N
IL-6
IL-7 N N N
IL-8 N N N N N
IL-9 N
IFNγ
IP-10 N
LIF N N N N N N
MCP-1
M-CSF N N N N
MIP-1α N
MIP-1β N N N
MIP-2 N N N N N N
PDGF N N N
TNF-α
VEGF N N N
  1. represents statistically significant increase in secretion compared with particle-free controls while represents statistically significant decreases in secretions. demonstrates no statistically significant change in secretion compared with non-exposed controls and N indicates instances where a cytokine species was not measured. Basic Fibroblast growth factor (bFGF), Chemokine (C-C-motif) ligand (CCL), Chemokine (C-X-C motif) ligand (CXCL), Granulocyte-colony stimulating factor (G-CSF), Interferon-γ neutralising (IFNγ), Interferon-γ-induced protein 10 (IP-10), Leukaemia inhibitory factor (LIF), Monocyte chemoattractant protein-1 (MCP-1), Macrophage colony stimulating factor (M-CSF), Macrophage inflammatory protein (MIP), Platelet-derived growth factor (PDGF), Tumour necrosis factor-α (TNF-α), Vascular endothelial growth factor (VEGF)