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Table 1 Physico-chemical characteristics of Fe3O4 and γ-Fe2O3 dSPION

From: In vitro detection of in vitro secondary mechanisms of genotoxicity induced by engineered nanomaterials

 

γ-Fe2O3 dSPION

Fe3O4 dSPION

Particle morphology

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Cubic crystalline structure with a primary particle size of 10 nm

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Cubic crystalline structure with a primary particle size of 10 nm

Chemical Composition

Fe2/Fe3 = 0.2

Fe2/Fe3 = 1.5

Hydrodynamic diameter and Zeta Potential

 Water

Size Range (nm)

37.84–531.52

11.70–164.2

Median size population (nm)

162.2

50.75

Polydispersal index

0.172

0.206

Zeta Potential (mV)

−9.48 ± 0.95

−13.5 ± 1.29

 10% serum medium

Size Range (nm)

18.17–220.10

28.21–141.8

Median size population (nm)

58.77

43.82

Polydispersal index

0.267

0.265

Zeta Potential

−3.38 ± 0.72

−4.77 ± 1.02

  1. γ-Fe2O3 and Fe3O4 dSPION chemical composition; hydrodynamic diameter displayed as size range (nm), median size population (nm) and polydispersity index and material zeta potential (mV)