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Table 1 Sample sizes for exposure of time-mated dams, pulmonary inflammation and reproductive parameters of male offspring

From: Effects of maternal inhalation of carbon black nanoparticles on reproductive and fertility parameters in a four-generation study of male mice

  Control Low High
F0
 Exposed time-mated females 20 20 20
F0
 Dams delivering litters 14 16 15
F0
 BAL fluid cells
  Non-littering females 4 4 4
  Littering females 5 9 13
F0
Saa3 expression in lung
  Non-littering females 6 4 5
  Littering females 11 12 13
F1
 Epididymal sperm parameters 11 11 12
 DSP 10 11 12
 SCSA 12 11 12
 Plasma testosterone 11 12 11
F2
 Epididymal sperm parameters 11 10 14
 DSP 11 10 14
 Plasma testosterone 11 10 10
F2a
 Epididymal sperm parameters 11 10 8
 DSP 11 9 5
 Plasma testosterone 11 6 4
F3
 Epididymal sperm parameters 9 10 10
 DSP 7 9 9
 Plasma testosterone 6 6 7
F4
 Epididymal sperm parameters 7   6
 DSP 7   6
 Plasma testosterone 7   6
  1. aF2 derived from the female germline