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Table 1 Sample sizes for exposure of time-mated dams, pulmonary inflammation and reproductive parameters of male offspring

From: Effects of maternal inhalation of carbon black nanoparticles on reproductive and fertility parameters in a four-generation study of male mice

 

Control

Low

High

F0

 Exposed time-mated females

20

20

20

F0

 Dams delivering litters

14

16

15

F0

 BAL fluid cells

  Non-littering females

4

4

4

  Littering females

5

9

13

F0

Saa3 expression in lung

  Non-littering females

6

4

5

  Littering females

11

12

13

F1

 Epididymal sperm parameters

11

11

12

 DSP

10

11

12

 SCSA

12

11

12

 Plasma testosterone

11

12

11

F2

 Epididymal sperm parameters

11

10

14

 DSP

11

10

14

 Plasma testosterone

11

10

10

F2a

 Epididymal sperm parameters

11

10

8

 DSP

11

9

5

 Plasma testosterone

11

6

4

F3

 Epididymal sperm parameters

9

10

10

 DSP

7

9

9

 Plasma testosterone

6

6

7

F4

 Epididymal sperm parameters

7

 

6

 DSP

7

 

6

 Plasma testosterone

7

 

6

  1. aF2 derived from the female germline