Fig. 4
From: A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations
Gene expression profiles in 3D lung microtissues after exposure to 10 μg/mL of test nanomaterials. a Gene expression in 3D lung microtissues exposed to 10 μg/mL carbon black, carbon nanotubes, or asbestos fibers for 4 or 7 days was quantified using PCR arrays. Both significant (p or q < 0.05, bold) and highly changed non-significant (italics) genes are included in the heat map. Significantly altered gene expression with a more than 2-fold change is shown as Venn diagrams organized by nanomaterial exposure after 4 days (b) and 7 days (c)