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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway

Fig. 2

Hemodynamic changes induced by SiNPs. (a) Control (b) 16.2 mg/kg·bw (c) Descending aorta velocity. (d) Cardiac output. The descending aorta velocity and cardiac output were decreased from 1278 mm/s to 894 mm/s and from 108 mL/min to 83 mL/min compared with the control in 16 mg/kg·bw group induced by SiNPs. Data were expressed as means ± S.D. from six independent experiments. *p < 0.05 compared with control without SiNPs and any mimics/inhibitor

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