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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Airport emission particles: exposure characterization and toxicity following intratracheal instillation in mice

Fig. 4

Illustration of dose-response linearity between instilled doses of airport-collected particles, NIST2975, NIST1650 and neutrophil influx in BAL. Increasing dose-response effects were confirmed with test for linear trend, where the alerting R2 (referred to as R2) is the fraction of the variance between group means that is accounted for by the linear trend (Altman/Sheskin, provided by GraphPad Prism). Data for NIST1650 was obtained from a previously published study [19]. Significant linear trends were verified for total cell numbers (not shown) and neutrophils in BAL fluid, with R2 between 0.76 and 0.95

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