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Table 1 Overview of samples

From: Airport emission particles: exposure characterization and toxicity following intratracheal instillation in mice

Particle type

Measurement

Instruments/Method

Relevant figures

Non-commercial airfield particles

(JEP)

Exposure characterization

1 ELPI

Figure 1:

Exposure characterization

4 DISCminis

Table 2:

Exposures and doses

1 NanoScan

Additional File 1: Figure S1 A:

Position of instruments Jet engine test facility

1 OPC

Additional File 1: Figure S1 B:

Background characterization

Micro INertial Impactor (MINI)

Results not shown

Emission characterization

Micro INertial Impactor (MINI)

Additional File 1: Figure S1 C:

Description of impacted aerosols and TEM images

Particle collection for physical and chemical characterization and mouse instillations

Electrostatic precipitator

Table 3:

PAH contents

Metal contents

Table 4:

JEP particles suspended in instillation vehicle

TEM (dropcast)

Table 5:

Size distribution

Additional File 1: Figure S1 D:

DLS figures

Fig. 2:

SEM images

Additional File 1: Figure S1E:

Elemental composition by EDS analysis

Commercial airport particles (CAP)

Exposure characterization

4 DISCminis

Figure 1:

Exposure characterization

1 NanoScan

Additional File 1: Figure S1 A:

Position of instruments

1 OPC

  

Emission characterization

Micro INertial Impactor (MINI)

Additional File 1: Figure S1 C:

Description of impacted aerosols and TEM images

Particle collection for physical and chemical characterization and mouse instillations

Electrostatic precipitator

Table 3:

PAH contents

Table 4:

Metal contents

CAP particles suspended in instillation vehicle

TEM, dropcast

Table 5:

Size distribution

Additional File 1: Figure S1 D:

DLS figures

Figure 2:

SEM images

Additional File 1: Figure S1 E:

Elemental composition by EDS analysis

Mouse instillations of JEP and CAP

Lung pathology

Histology

Figure 3:

Histopathology of lung sections

Cellular composition in the lungs

Broncho-alveolar lavage (BAL)

Table 6:

BAL fluid cell composition

Figure 4:

Dose-response relationship of instilled particles

Figure 5:

Neutrophil influx

Additional File 2: Figure S2 A:

Scatter plots of cellular influx

Eosinophil influx

Serum Amyloid A levels in tissues

mRNA expression

Figure 6:

SAA day 1

Additional File 2: Figure S2 B:

SAA day 28 and 90

DNA damage

DNA strand breaks (Comet Assay)

Figure 7:

Tail Length

Additional File 2: S2C:

% DNA in Tail and data table