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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

Fig. 1

Study population and experimental protocol. Flowchart describing the number of animals subjected to the different experimental procedures before and after intra-tracheal instillation of saline solution (CTRL group) or saline solution added with TiO2, at a final concentration of 2 mg/kg (TiO2-NP group). * timepoints for oxidative stress and inflammation; § timepoints for real-time PCR analysis; # timepoints for PIXE. For more details see “Outline of the experimental protocols” section

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