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Table 1 Hemodynamic study

From: Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

  CTRL (n = 9) TiO2-NP (n = 11)
Heart rate (beats/min) 188 ± 5 190 ± 5
Systolic arterial BP (mmHg) 197.5 ± 2.12 198.16 ± 7.08
Diastolic arterial BP (mmHg) 122.4 ± 4.36 123.0 ± 4.92
LVSP (mmHg) 195.9 ± 2.90 195.4 ± 5.96
LVEDP (mmHg) 6.51 ± 0.55 8.32 ± 0.64*
+dP/dtmax (mmHg/s) 9639.6 ± 86.37 8190.1 ± 264.5*
-dP/dtmax (mmHg/s) − 7790.6 ± 117.7 − 6608.2 ± 91.28*
IVCT (s) 0.020 ± 0.0002 0.022 ± 0.0003*
  1. Values are means ± standard error of the mean (SEM)
  2. Hemodynamic measurements were performed at 7th week, before sacrifice. Unpaired Student’s t-test
  3. BP blood pressure, LVSP left ventricular systolic pressure, LVEDP left ventricular end-diastolic pressure, +dP/dtmax maximal rate of left ventricular (LV) pressure rise, −dP/dtmax maximal rate of LV pressure decline, IVCT isovolumic contraction time
  4. *p < 0.05 vs CTRL