Skip to main content

Table 1 Hemodynamic study

From: Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

 

CTRL (n = 9)

TiO2-NP (n = 11)

Heart rate (beats/min)

188 ± 5

190 ± 5

Systolic arterial BP (mmHg)

197.5 ± 2.12

198.16 ± 7.08

Diastolic arterial BP (mmHg)

122.4 ± 4.36

123.0 ± 4.92

LVSP (mmHg)

195.9 ± 2.90

195.4 ± 5.96

LVEDP (mmHg)

6.51 ± 0.55

8.32 ± 0.64*

+dP/dtmax (mmHg/s)

9639.6 ± 86.37

8190.1 ± 264.5*

-dP/dtmax (mmHg/s)

− 7790.6 ± 117.7

− 6608.2 ± 91.28*

IVCT (s)

0.020 ± 0.0002

0.022 ± 0.0003*

  1. Values are means ± standard error of the mean (SEM)
  2. Hemodynamic measurements were performed at 7th week, before sacrifice. Unpaired Student’s t-test
  3. BP blood pressure, LVSP left ventricular systolic pressure, LVEDP left ventricular end-diastolic pressure, +dP/dtmax maximal rate of left ventricular (LV) pressure rise, −dP/dtmax maximal rate of LV pressure decline, IVCT isovolumic contraction time
  4. *p < 0.05 vs CTRL
Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us