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Table 2 Tibial length, cardiac anatomy and morphometric analysis

From: Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

 

CTRL (n = 9)

TiO2-NP (n = 11)

Tibial length (mm)

38.2 ± 0.95

35.7 ± 0.25 *

BW (g)

359.3 ± 6.47

356.1 ± 5.70

LVW (mg)

1200 ± 25.50

1119.13 ± 27.91 *

LVW/BW (mg/g)

3.39 ± 0.10

3.16 ± 0.11

LV mass (mm3)

1132.1 ± 24.06

1055.8 ± 26.33 *

LV wall thickness (mm)

2.28 ± 0.09

2.26 ± 0.06

LV chamber diameter (mm)

7.43 ± 0.40

7.68 ± 0.25

LV chamber length (mm)

15.44 ± 0.50

15.11 ± 0.42

LV chamber volume (mm3)

361.3 ± 38.16

469.3 ± 31.29 *

LV mass/chamber volume

3.11 ± 0.33

2.39 ± 0.16

Total fibrosis (%)

7.64 ± 1.11

15.44 ± 3.09 *

Diffuse Fibrosis (%)

4.24 ± 0.82

11.69 ± 3.18 *

Perivascular Fibrosis (%)

3.59 ± 0.49

4.69 ± 0.45

  1. Values are means ± SEM
  2. Unpaired Student’s t-test
  3. BW body weight measured before sacrifice, LV left ventricular, LVW left ventricular weight
  4. *p < 0.05 vs CTRL