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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Iron oxide nanoparticles induce reversible endothelial-to-mesenchymal transition in vascular endothelial cells at acutely non-cytotoxic concentrations

Fig. 4

PSC-Fe2O3 induced ·OH production by peroxidase-like activities. a Intracellular ROS of HUVEC. b HO-1 gene expression of HUVEC. c Extracellular ROS of HUVEC. d Extracellular H2O2. e PSC-Fe2O3 catalyzed H2O2 into ·OH in a concentration dependent manner. f The ESR spectrum of DMPO / ·OH adduct. Data are mean ± SD, n = 3, one-way ANOVA with Dunnett’s multiple comparisons test, *p < 0.05, **p < 0.01, significant compared to control

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