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Table 4 Cell Cycle Analysis

From: Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotubes elicit genotoxicity in human lung epithelial cells

Cell Type Exposure time (h) Treatment %G1 %S %G2
BEAS-2B 24 Control 38 ± 2 23 ± 2 37 ± 3
Arsenic 45 ± 3* 17 ± 2* 35 ± 2
MWCNT-7 42 ± 4 33 ± 3* 25 ± 2*
MWCNT-HT 36 ± 2 34 ± 5*¥ 27 ± 4*
MWCNT-ND 39 ± 2 28 ± 4¥ 30 ± 3*
SAEC 24 Control 61 ± 2 29 ± 3 8 ± 1
Arsenic 64 ± 3 25 ± 4* 9 ± 1
MWCNT-7 76 ± 4* 10 ± 5* 10 ± 1
MWCNT-HT 81 ± 1*¥ 5 ± 1*¥ 11 ± 1*
MWCNT-ND 75 ± 1*¥ 14 ± 1*¥ 10 ± 1*
SAEC 72 Control 74 ± 5 15 ± 6 11 ± 1
Arsenic 72 ± 2 7 ± 1* 18 ± 1*
MWCNT-7 56 ± 2*¥ 31 ± 3* 13 ± 1
MWCNT-HT 70 ± 6 21 ± 6*¥ 10 ± 1
MWCNT-ND 68 ± 5* 21 ± 5* 11 ± 2
  1. This table shows the mean percentage of cells in the G1, S, and G2 phase of the cell cycle measured via flow cytometry. The 24 h exposures used 24 μg/mL MWCNT doses whereas the 72 h exposure used 2.4 μg/mL MWCNT doses. BEAS-2B used 5 μM arsenic as a positive control whereas SAEC used 10 μM arsenic as a positive control. *Significantly different from control, p < 0.05 ¥Significantly different from other MWCNT materials at same dose, p < 0.05; ± SD