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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies

Fig. 3

Cytotoxicity of AgNPs. a Cell death of NCTC-1469, L-02, Hepa1–6 and HepG2 cells with or without AgNPs-treatment at 1, 4, 10, 20 or 50 μg/mL analyzed using flow cytometer. b Heatmap of cell viability. HepG2 cells were treated with AgNPs at 1, 2, 4, 8, 10, 20, 30 or 50 μg/mL for 1, 2, 4, 6, 24 and 48 h, respectively. c Hyperspectral images of untreated and AgNPs-treated HepG2 cells at 4 or 10 μg/mL for 24 h. The yellow arrow denotes the internalized AgNPs in cytoplasm

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