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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies

Fig. 7

Depletion of GST activity induced more serious cytotoxicity. a Cell viability of untreated and AgNPs-treated HepG2 cells at 4, 8, 10, 20 or 50 μg/mL for 24 h without or with EA-treatment at 20, 50 or 100 μM (n = 5). b Cell death of untreated and AgNPs-treated HepG2 cells at 20 μg/mL for 24 h without or with EA-treatment at 100 μM. c Intracellular ROS generation in untreated and AgNPs-treated HepG2 cells at 1, 2, 4, 10 or 20 μg/mL for 3 h without or with EA-treatment at 100 μM (n = 5). H2O2-treatment was used as positive control. Asterisk (*) denotes P < 0.05

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