Particle and Fibre Toxicology

Table 1 Physicochemical characterization of AgNPs in various media

From: Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies

	DW	PBS	ALF	DMEM	CCM
Diameter measured by TEM (nm) ^c	19.4 ± 3.5 ^a	34.6 ± 14.4 ^a	21.0 ± 5.0 ^a	–	19.7 ± 3.5 ^a
Diameter measured by TEM (nm) ^c	19.8 ± 4.3 ^b	23.5 ± 4.7 ^b	22.3 ± 5.9 ^b	–	19.8 ± 4.2 ^b
Hydrodynamic diameter (nm)	58.1 ± 0.3 ^a	96.6 ± 1.6 ^a	71.1 ± 3.1 ^a	113.2 ± 11.6 ^a	103.6 ± 7.1 ^a
Hydrodynamic diameter (nm)	60.2 ± 0.4 ^b	67.6 ± 3.2 ^b	96.9 ± 4.2 ^b	402.1 ± 61.7 ^b	82.6 ± 0.4 ^b
Zeta-potential (mV)	−1.5 ± 0.4 ^a	− 17.4 ± 0.3 ^a	− 11.9 ± 1.7 ^a	− 11.8 ± 0.8 ^a	−14.5 ± 0.5 ^a
Zeta-potential (mV)	− 1.5 ± 0.6 ^b	−27.9 ± 0.8 ^b	−14.9 ± 1.6 ^b	−13.0 ± 0.3 ^b	−16.2 ± 0.2 ^b
Polydispersity index (PDI)	0.15 ± 0.01 ^a	0.46 ± 0.03 ^a	0.45 ± 0.07 ^a	0.51 ± 0.09 ^a	0.40 ± 0.03 ^a
Polydispersity index (PDI)	0.14 ± 0.00 ^b	0.41 ± 0.01 ^b	0.49 ± 0.10 ^b	0.76 ± 0.13 ^b	0.28 ± 0.01 ^b
λ_max (nm)	417 ^a	415 ^a	415 ^a	416 ^a	418 ^a
λ_max (nm)	417 ^b	403 ^b	408 ^b	420 ^b	423 ^b

^at = 0 h; ^b t = 24 h. ^c AgNPs counting (n = 100)

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