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Table 1 Synthesis, physicochemical parameters, and silanol content of wet chemistry made silica, FSP-made silicas, and commercial fumed silica

From: Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity

Silica type HDMSO Molarity (M) x/y Enthalpy (MJ/kg) SSA (m2/g) dBET (nm) Density (g/cc) Silanol content (mmol OH/g) SiOx (x) Si-OH/SiO Ratio
  WetChem SiO2 N/A N/A N/A 500a 4.9 2.4 ± 0.0 5.9 ± 0.0a 2.11 ± 0.01 0.65 ± 0.09
Cold Silica FSP SiO2–5/5 0.5 5/5 10.9 152 15.4 2.6 ± 0.1 6.1 ± 0.1 2.01 ± 0.01 0.45 ± 0.06
FSP SiO2−3/5 0.8 3/5 8.9 186a 14.7a 2.2 ± 0.0 5.2 ± 0.1a 2.17 ± 0.01 0.43 ± 0.06
FSP SiO2−4/5 0.8 4/5 10.1 217a 12.6a 2.2 ± 0.0 4.8 ± 0.1a 2.17 ± 0.04 0.35 ± 0.05
Hot Silica FSP SiO2−9/3 0.8 9/3 16.6 217a 12.6a 2.2 ± 0.0 2.0 ± 0.1a 2.06 ± 0.05 0.13 ± 0.02
FSP SiO2−11/3 0.8 11/3 17.8 186a 14.7a 2.2 ± 0.0 1.6 ± 0.1a 2.11 ± 0.05 0.11 ± 0.01
  Comm. fumed SiO2 N/A N/A N/A 206a 9.0a 3.2 ± 0.1 0.7 ± 0.0a 2.02 ± 0.04 0.07 ± 0.01
  1. aThe values are from reference [18]
  2. SSA Specific surface area, dBET Diameter determined by Brunauer-Emmett-Teller nitrogen adsorption, FSP Flame spray pyrolysis; The nomenclature used in this table for Silica NPs indicates the method of synthesis (FSP), the molarity, and the precursor/dispersion flows ratio x/y