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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

Fig. 3

IL6, TNF-α, IL8 and IL10 levels from NM exposed human liver MT. The tissues were exposed to cell medium (c) or repeated concentrations of NMs (NM treatments 1.25–5 μg/ml) for up to 3 weeks - a IL6, b TNF-α, c IL8 and d IL10. The values represent mean ± SEM (n = 3) with significance indicated by * p < 0.05 and ** p < 0.005 of NM-induced effects compared to negative control

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