Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate

Table 2 Main physical and chemical properties of investigated NMs (adapted and reproduced from 18 to 20)

NM code	NM type	Phase	Primary size (nm) (XRD)	Surface area [m²/g] (BET)	Known coating	Mean size in liver maintenance medium (DLS) (nm)^a
JRCNM01005a	TiO₂	Rutile-anatase	15–24	46	None	224.6 233.7 238.3
JRCNM01101a	ZnO	–	152	15	Triethoxy-caprlsilane	250.3 255.8 255.4
NM212	CeO₂	Irregular and non-homogeneous - cubic cerionite	49	27	None	274.5 269.3 258.9
DQ12	Silica	Quartz	–	10.1	None	479.8 468.5 466.9

ISSN: 1743-8977