Skip to main content
Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Silicon dioxide nanoparticles induce insulin resistance through endoplasmic reticulum stress and generation of reactive oxygen species

Fig. 4

RNA-sequencing results show that oral administration of 100 mg/kg bw of SiO2 NPs (nanoparticles) significantly upregulated the expression of 517 genes and downregulated the expression of 183 genes at weeks 10 and 18. These genes were enriched in 311 GO (Gene Ontology) terms, including 258 BP (Biological Process) terms, 28 CC (Cellular Component) terms, and 25 MF (Molecular Function) terms. a Genes with significant changes in expression. b GO terms (BP, CC, and MF from left to right). c Relational network of all GO terms (BP, CC, and MF from left to right). (n = 3)

Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us