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Table 1 Size characterization of SAS dispersed in 0.05% Bovine Serum Albumin (BSA)

From: Is aggregated synthetic amorphous silica toxicologically relevant?

Stock suspensions

Stock concentration (mg/mL)

TEM

DLS

Mean ECD (nm)

Mean Feret min (nm)

Z-average (nm)

DE-AGGR

2.56

100 ± 14

28 ± 0.6

264

AGGR

2.56

2000

600

12,530

SuperN

0.64

600a

n/a

3953

PREC

1.92

750a

n/a

3332

  1. Mean equivalent circle diameter (ECD) and mean feret minimum (Feret min) measured by TEM; Mean hydrodynamic diameter (Z-average) by DLS; n/a-not available. asize was measured manually using the arbitrary line measurement tool of the iTEM software