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Table 2 Bronchoalveolar lavage fluid cell counts in Sprague Dawley rats

From: Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats

 

Total cell number (106)

Macrophages (106)

Neutrophils (106)

Week 12 – exposure

 Air + Reg

3.83 + 0.4

3.83 + 0.4

0.00 + 0.0

 Air + HF

4.46 + 0.5

4.46 + 0.5

0.00 + 0.0

 GMA-SS + Reg

92.1 + 13.0 ab

77.6 + 11.0 ab

14.5 + 5.2 abc

 GMA-SS + HF

68.0 + 9.7 ab

65.3 + 9.7 ab

2.71 + 1.3 ab

Week 24 – recovery

 Air + Reg

4.66 + 0.5

4.65 + 0.5

0.01 + 0.01

 Air + HF

3.51 + 0.4

3.50 + 0.4

0.01 + 0.01

 GMA-SS + Reg

6.94 + 1.1b

4.99 + 0.5

0.16 + 0.01

 GMA-SS + HF

4.92 + 0.8

4.87 + 0.7

0.06 + 0.02

  1. Total cell number, macrophages and neutrophils in the bronchoalveolar lavage fluid from Sprague Dawley rat lungs at week 12 after a 5-week exposure to 20 mg/m3 of GMA-SS; and at week 24 after a 12 week recovery period. Mean ± SD (n = 6). Significant effects are highlighted in bold
  2. aSignificantly different from Air+Reg diet (p < 0.05)
  3. bSignificantly different from Air+HF diet (p < 0.05)
  4. cSignificantly different from GMA-SS + HF diet (p < 0.05)
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Particle and Fibre Toxicology

ISSN: 1743-8977

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