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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Combination of the BeWo b30 placental transport model and the embryonic stem cell test to assess the potential developmental toxicity of silver nanoparticles

Fig. 5

Concentration–response curves for cytotoxicity towards mESCs and for the effect on differentiation into contracting cardiomyocytes of: a (LA) AgNPs, b (Cit) AgNPs, c (BEPI) AgNPs, d (Ag2S) NPs, and e AgNO3. The viability of mESCs (right y-axis) was assessed using the ATPlite assay after 24 h and 120 h of exposure. The differentiation of mESCs into contracting cardiomyocytes (left y-axis) was scored after microscopical evaluation. Values are given as a percentage of the control (mean ± SD; n = 3)

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