Fig. 5
Effects of PM2.5 exposure on plasmalogen levels and relevant signals in the liver. A, Total plasmalogen content in the hepatic lipid extracts in male and female mice. B, Major plasmalogen species in the hepatic lipid extracts of female mice. C and D, mRNA levels of genes involved in plasmalogen synthesis, FADs and mitochondrial and peroxisomal FAO in the liver of male (C) and female (D) mice. E-G, Representative bands (E) and analyzed protein levels of CPT1αand ACOX1 in the liver of male (F) and female (G) mice. *P < 0.05, **P < 0.01 for each comparison. n = 5 for lipidomic analysis, n = 7–9 for mRNA examination, and n = 6 for protein examination