Fig. 3
Time-dependent gene expression of CXCL8, IL-6, IL-1α, IL-1β and TNF-α on the apical and basolateral side of 3D tri-cultures after Min-U-Sil exposure. The figure shows gene expression 3, 6, 10 and 20 h after exposure to Min-U-Sil (96 and 192 μg/cm2). Gene expression was determined by qPCR, and presented as fold increase compared to control. Data represent the mean +/− SEM of 3–5 independent experiments. *Statistical significant difference from control at the same time-point P < 0.05