Fig. 4
Time-dependent gene expression of ICAM-1 and Selectin E on the apical and basolateral side of 3D tri-cultures after Si10 or Min-U-Sil exposure. The figure shows gene expression 3, 6, 10 and 20 h after exposure to 12 and 24 μg/cm2 Si10 (a-d) or 96 and 192 μg/cm2 Min-U-Sil (e-h). Gene expression was determined by qPCR, and is presented as fold increase compared to control. Data represent the mean +/− SEM of 3–5 independent experiments. *Statistical significant difference from control at the same time-point P < 0.05