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Fig. 11 | Particle and Fibre Toxicology

Fig. 11

From: Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm silver nanoparticle aerosols in healthy adult rats after a single 1½-hour inhalation exposure

Fig. 11

Fecal excretion of [105Ag]Ag and of [195Au]Au activity. Comparison of fecal excretion rates (panels a and b) and cumulative excretion (panels c and d), respectively. Fractional rates are normalized to ILD. For [105Ag]AgNP n = 4; for [195Au]AuNP n ≤ 6. In panel e the fecal excretion of [105Ag]Ag is shown which is attributed to precipitated [105Ag]Ag-salt, that had crossed the ABB into the blood and was eliminated via hepato-biliary clearance into the GIT. It is based on the difference between panels A and B assuming that both inhaled NP materials are cleared with similar fractional rates

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Particle and Fibre Toxicology

ISSN: 1743-8977

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