Skip to main content
Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Oxygenated polycyclic aromatic hydrocarbons from ambient particulate matter induce electrophysiological instability in cardiomyocytes

Fig. 5

Biochemical effects of PAHs and oxy-PAHs. Cardiomyocytes were treated with control (DMSO), ANT, AQ, BaA, or BAQ at the indicated concentrations for 24 h. a Ca2+-dependent ATPase activity was assessed by measuring the quantity of inorganic phosphate (Pi) (n = 4). b Protein oxidation was assayed by measuring carbonyl formation (n = 4). c MDA concentration was assessed by measuring TBARS and normalized to the amounts of proteins (n = 4). d The expression levels of phosphorylated ERK1/2 and Akt were analyzed by western blotting (n = 4) and the protein levels were normalized to total ERK or Akt levels, respectively. H2O2 (200 nM) was used as a positive control. All values are represented as mean ± SD. *P < 0.05 or **P < 0.01 compared with control

Back to article page