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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells

Fig. 2

Effects of PM on cytotoxicity and cellular metabolism in hOM cultures. a hOM cells exposed to PM1–0.2, PM2.5–1 or PM10–2.5 for 24 h, after which cell death was measured by the LDH release assay. Results were normalised by lysed cell control, n = four donors. Metabolic activity was measured by the MTT reduction assay of hOM cultures. Results were normalised to the vehicle, n = four donors. ** p < 0.01, *** p < 0.001. c Caspase-3/7 signal intensity in live single cells of a representative culture exposed to all three PM, n = three experimental replicates

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