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Table 3 Beas-2B Cytotoxicity Summarization

From: Carbon nanotube filler enhances incinerated thermoplastics-induced cytotoxicity and metabolic disruption in vitro

Filter Status

Time

Treatment

ED50 (μg/cm2)

Potency ED50P/ED50CNT

PI-

WST1

PI-

WST1

Unfiltered

24

PC

2.28

5.34

1.70***

1.92***

24

PC-CNT

1.34

2.78

24

PU

> 4.0

> 4.0

N.D.

N.D.

24

PU-CNT

> 4.0

> 4.0

48

PC

1.90

3.52

1.98***

1.86***

48

PC-CNT

0.96

1.89

48

PU

> 4.0

> 4.0

N.D.

N.D.

48

PU-CNT

> 4.0

> 4.0

Filtered

24

PC

> 4.0

> 8.0

N.D.

N.D.

24

PC-CNT

> 4.0

> 8.0

24

PU

> 4.0

> 4.0

N.D.

N.D.

24

PU-CNT

> 4.0

> 4.0

48

PC

> 4.0

> 8.0

N.D.

N.D.

48

PC-CNT

> 4.0

> 8.0

48

PU

> 4.0

> 4.0

N.D.

N.D.

48

PU-CNT

> 4.0

> 4.0

  1. PI- – Cytotoxicity derived from live-cell imaging
  2. WST1 – Cytotoxicity derived from the WST1 method
  3. ED50 – Modeled deposited dose causing 50% of reported cytotoxicity compared to untreated controls
  4. Potency ED50p/ED50CNT – Relative deposited dose causing 50% of cytotoxicity among pristine incinerated thermoplastic (ED50p) compared to CNT-containing analog (ED50CNT) at the same time point. Potency comparisons across time points were not made
  5. N.D. ED50p/ED50CNT Potency value could not be determined
  6. ***p < 0.001 of compared to pristine incinerated thermoplastic at the same time point