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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Activation of synovial fibroblasts from patients at revision of their metal-on-metal total hip arthroplasty

Fig. 1

Synovial tissues from primary THA patients and patients with metal-on-metal THA implants. a Macroscopic evaluation of synovial membrane isolated from primary and revision MoM THA implants. Scale bar indicates 50 μm. b Collagen visualized by picrosirius red and c collagen I visualized by immunohistochemistry staining with quantification showed in e and f. d α-SMA positive fibroblasts in synovial membrane tissue with quantification shown in g. Scale bar indicates 200 μm in (b-d). Data was obtained from 8 primary THA and 8 MoM tissue samples. For each slide/patient, 10 random fields were imaged for analysis. Bars represent mean + SEM; unpaired t-test, ** p < 0.01, *** p < 0.001

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Particle and Fibre Toxicology

ISSN: 1743-8977

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