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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Activation of synovial fibroblasts from patients at revision of their metal-on-metal total hip arthroplasty

Fig. 4

Contractile forces and cell stiffness of fibroblasts from patients during primary THA and at revision from a MoM THA. a Bright field images of individual cell (i) and corresponding stress magnitude maps (ii); b Quantification of cellular contractile force of fibroblasts from the cells of individual groups; n = 40 for each group (each data point represents the mean value of 5 cells analysed for each patient). c Schematic of AFM setup for measuring cell stiffness. d Image showing the AFM cantilever and synovial fibroblasts. e Quantification of cell stiffness for primary and MoM fibroblasts; n = 40 (each data point represents the mean value of 5 cells analysed for each patient); unpaired Student’s t-test. *p < 0.05

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